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Interferon-gamma (IFN-γ) and prostaglandin E(2)(PGE(2)) regulate differently IL-12 production in human intestinal lamina propria mononuclear cells (LPMC)
IL-12 modulates Th1 immune response during chronic colitis. Mechanisms regulating IL-12 synthesis in human intestine are poorly understood. The aim of this study was to investigate the effect of IFN-γ and PGE(2) on lipopolysaccharide (LPS)-stimulated LPMC IL-12 production. Normal LPMC cultures were...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905357/ https://ncbi.nlm.nih.gov/pubmed/10469049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00991.x |
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