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Interferon-gamma (IFN-γ) and prostaglandin E(2)(PGE(2)) regulate differently IL-12 production in human intestinal lamina propria mononuclear cells (LPMC)

IL-12 modulates Th1 immune response during chronic colitis. Mechanisms regulating IL-12 synthesis in human intestine are poorly understood. The aim of this study was to investigate the effect of IFN-γ and PGE(2) on lipopolysaccharide (LPS)-stimulated LPMC IL-12 production. Normal LPMC cultures were...

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Autori principali: Monteleone, G, Parrello, T, Monteleone, I, Tammaro, S, Luzza, F, Pallone, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905357/
https://ncbi.nlm.nih.gov/pubmed/10469049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00991.x
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