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Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses

In this study we have tested the concept of using wild-type p53 gene for immunotherapy of cancer. Dendritic cells (DC) were transduced with a human wild-type p53 containing recombinant adenovirus (Ad-p53). About a half of DC transduced with this virus expressed p53 protein by FACS analysis 48 h afte...

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Detalhes bibliográficos
Main Authors: Ishida, T, Chada, S, Stipanov, M, Nadaf, S, Ciernik, F I, Gabrilovich, D I, Carbone, D P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905349/
https://ncbi.nlm.nih.gov/pubmed/10444254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00913.x
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