Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA)

A strategy of gene therapy using IL-4 or IL-13 xenogeneic transfected cells encapsulated into permeable hollow fibres (HF) was used to treat CIA. Hydrogel-based hollow fibres were obtained from AN-69 copolymer, already known for its biocompatibility and tolerance in rodents. Permeability to IL-4 and...

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Detalhes bibliográficos
Main Authors: Bessis, N, Honiger, J, Damotte, D, Minty, A, Fournier, C, Fradelizi, D, Boissier, M-C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905333/
https://ncbi.nlm.nih.gov/pubmed/10444273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00959.x
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