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HBV-specific immune defect in chronic hepatitis B (CHB) is correlated with a dysregulation of pro- and anti-inflammatory cytokines

The aim of this study was to examine the immunomodulating effects of rhIL-12 on the immune response induced by hepatitis B virus (HBV) antigens in clinical subgroups of patients with HBV infection. Peripheral blood mononuclear cells (PBMC) of 80 patients were stimulated with HBsAg, HBcAg, pre-S1Ag a...

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Main Authors: Schlaak, J F, Tully, G, Löhr, H F, Gerken, G, Meyer Zum Büschenfelde, K-H
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905245/
https://ncbi.nlm.nih.gov/pubmed/10193426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00812.x
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