T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC)

PBC is characterized by T cell-mediated destruction of the biliary epithelial cells lining the small intrahepatic bile ducts. The E2 and E3 binding protein (E3BP (protein X)) components of pyruvate dehydrogenase complex (PDC) are disease-specific autoantigens in PBC. Attempts to localize the T cell...

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Detalhes bibliográficos
Main Authors: PALMER, J M, DIAMOND, A G, YEAMAN, S J, BASSENDINE, M F, JONES, D E J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905223/
https://ncbi.nlm.nih.gov/pubmed/10209517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00803.x
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