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Detection of antibodies directed against the cytoplasmic region of the human acetylcholine receptor in sera from myasthenia gravis patients

The nicotinic acetylcholine receptor (AChR) is the autoantigen in the human autoimmune disease myasthenia gravis (MG). Anti-AChR antibodies in MG sera bind mainly to conformational epitopes, therefore the determination of their specificities requires the use of native AChR. Antibody competition stud...

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Main Authors: TZARTOS, S J, REMOUNDOS, M
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905210/
https://ncbi.nlm.nih.gov/pubmed/10209519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00846.x
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