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Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-α) production acting on leucocytes resembling immature dendritic cells

Patients with active SLE often have an ongoing production of IFN-α. We therefore searched for an endogenous IFN-α-inducing factor (IIF) in SLE patients and found that their sera frequently induced production of IFN-α in cultures of peripheral blood mononuclear cells (PBMC) from healthy blood donors,...

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Bibliographic Details
Main Authors: Vallin, H, Blomberg, S, Alm, G V, Cederblad, B, RÖnnblom, L
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905199/
https://ncbi.nlm.nih.gov/pubmed/9933442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00772.x
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