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Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-α) production acting on leucocytes resembling immature dendritic cells
Patients with active SLE often have an ongoing production of IFN-α. We therefore searched for an endogenous IFN-α-inducing factor (IIF) in SLE patients and found that their sera frequently induced production of IFN-α in cultures of peripheral blood mononuclear cells (PBMC) from healthy blood donors,...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Blackwell Science Inc
1999
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905199/ https://ncbi.nlm.nih.gov/pubmed/9933442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00772.x |
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