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Are circulating neutrophils intravascularly activated in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides?

Vascular injury in vasculitis may be due to activation of circulating neutrophils resulting in their increased adhesiveness to locally activated endothelium (Shwartzman phenomenon). Previously, we demonstrated up-regulation of endothelial intercellular adhesion molecule-1 (ICAM-1) and vascular cell...

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Main Authors: MULLER KOBOLD, A C, MESANDER, G, STEGEMAN, C A, KALLENBERG, C G M, COHEN TERVAERT, J W
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905131/
https://ncbi.nlm.nih.gov/pubmed/9844062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00748.x
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