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Expression, characterization, processing and immunogenicity of an insulin-dependent diabetes mellitus autoantigen, IA-2, in Sf-9 cells

Autoantibodies to a 64-kD protein and a 40-kD tryptic fragment from pancreatic islets have been detected at high frequency in the sera of patients with insulin-dependent diabetes mellitus (IDDM). IA-2, a newly isolated transmembrane protein tyrosine phosphatase, is a major islet cell autoantigen in...

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Sonraí Bibleagrafaíochta
Main Authors: Xie, H, Deng, Y J, Notkins, A L, Lan, M S
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 1998
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905060/
https://ncbi.nlm.nih.gov/pubmed/9737664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00676.x
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