IL-10 up-regulates nitric oxide (NO) synthesis by lipopolysaccharide (LPS)-activated macrophages: improved control of Trypanosoma cruzi infection

We examined the effects of IL-10 on tumour necrosis factor-alpha (TNF-α) and NO production by LPS-activated macrophages and on the ability of these cells to control Trypanosoma cruzi infection. We first observed that the addition of rIL-10 to macrophages of the J774 cell line decreased their synthes...

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Detalhes bibliográficos
Main Authors: Jacobs, F, Chaussabel, D, Truyens, C, Leclerq, V, Carlier, Y, Goldman, M, Vray, B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
Assuntos:
Immunity to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905023/
https://ncbi.nlm.nih.gov/pubmed/9697984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00637.x
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