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Deoxyspergualin preferentially inhibits the growth and maturation of anti-CD40-activated surface IgD(+) B lymphocytes

Deoxyspergualin (DSG), an analogue of spermidin, is a potent immunosuppressive drug with an action quite distinct from that of cyclosporin, rapamycin, or FK506. In this study we investigated the effect of DSG and methyldeoxyspergualin (MeDSG) on the proliferation and differentiation of human B cells...

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Autori principali: Morikawa, K, Nemoto, K, Miyawaki, T, Morikawa, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904992/
https://ncbi.nlm.nih.gov/pubmed/9649221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00602.x
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