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V(H) usage and somatic hypermutation in peripheral blood B cells of patients with rheumatoid arthritis (RA)

The human antibody repertoire has been demonstrated to have a marked V-gene-dependent bias that is conserved between individuals. In RA patients, certain heavy chain V genes (V(H)) have been found to be preferentially used for encoding autoantibodies. To determine if such preferential use of V(H) ge...

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Detalhes bibliográficos
Main Authors: Huang, S-C, Jiang, R, Hufnagle, W O, Furst, D E, Wilske, K R, Milner, E C B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904985/
https://ncbi.nlm.nih.gov/pubmed/9649224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00580.x
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