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Pentoxifylline decreases in vivo and in vitro tumour necrosis factor-alpha (TNF-α) production in lepromatous leprosy patients with erythema nodosum leprosum (ENL)

Increasing evidence has implicated TNF-α as a pivotal molecule involved in the systemic inflammatory manifestations of ENL, an acute inflammatory complication that may occur in the chronic course of leprosy. In the present study, the mechanism of action of pentoxifylline (PTX) as an alternative ther...

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Détails bibliographiques
Auteurs principaux: Sampaio, E P, Moraes, M O, Nery, J A C, Santos, A R, Matos, H C, Sarno, E N
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904921/
https://ncbi.nlm.nih.gov/pubmed/9486396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00510.x
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