Pentoxifylline decreases in vivo and in vitro tumour necrosis factor-alpha (TNF-α) production in lepromatous leprosy patients with erythema nodosum leprosum (ENL)

Increasing evidence has implicated TNF-α as a pivotal molecule involved in the systemic inflammatory manifestations of ENL, an acute inflammatory complication that may occur in the chronic course of leprosy. In the present study, the mechanism of action of pentoxifylline (PTX) as an alternative ther...

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Autors principals: Sampaio, E P, Moraes, M O, Nery, J A C, Santos, A R, Matos, H C, Sarno, E N
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1998
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904921/
https://ncbi.nlm.nih.gov/pubmed/9486396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00510.x
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