Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the immediate-early IES (US3) promoter from human cytomegalovirus.

Ítems similars

• The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signal.
  per: Pizzorno, M C, et al.
  Publicat: (1991)
• IE2 protein is insufficient for transcriptional repression of the human cytomegalovirus US3 promoter.
  per: Biegalke, B J
  Publicat: (1997)
• Characterization of the Transcriptional Repressive Element of the Human Cytomegalovirus Immediate-Early US3 Gene
  per: Biegalke, Bonita J.
  Publicat: (1998)
• Evaluation of Interactions of Human Cytomegalovirus Immediate-Early IE2 Regulatory Protein with Small Ubiquitin-Like Modifiers and Their Conjugation Enzyme Ubc9
  per: Ahn, Jin-Hyun, et al.
  Publicat: (2001)
• An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter.
  per: Macias, M P, et al.
  Publicat: (1993)