Chemoattractant-induced release of elastase by lipopolysaccharide (LPS)-primed neutrophils; inhibitory effect of the anti-inflammatory drug nimesulide

Human neutrophils, pre-exposed to low concentrations (1–10 ng/ml) of bacterial LPS in the presence of 1% autologous serum, released elastase activity in response to n-formyl-met-leu-phe (fMLP). Both cell incubation with LPS without subsequent fMLP stimulus and fMLP stimulation without prior exposure...

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Autori principali: OTTONELLO, L, BARBERA, P, DAPINO, P, SACCHETTI, C, DALLEGRI, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1997
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Editorial Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904789/
https://ncbi.nlm.nih.gov/pubmed/9353161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.5011400.x
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