Experimental immunization with anti-rheumatic bacterial extract OM-89 induces T cell responses to heat shock protein (hsp)60 and hsp70; modulation of peripheral immunological tolerance as its possible mode of action in the treatment of rheumatoid arthritis (RA)

OM-89 is a bacterial (Escherichia coli) extract used for oral administration in the treatment of RA. Given the evidence that immunity to bacterial heat shock antigens plays a critical role in the immunomodulation of arthritis and possibly inflammation in general, the purpose of the present studies w...

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Main Authors: BLOEMENDAL, A, VAN DER ZEE, R, RUTTEN, V P M G, VAN KOOTEN, P J S, FARINE, J C, VAN EDEN, W
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1997
Assuntos:
Editorial Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904786/
https://ncbi.nlm.nih.gov/pubmed/9353151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4841378.x
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