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Anti-CD2 (OX34) MoAb treatment of adjuvant arthritic rats: attenuation of established arthritis, selective depletion of CD4(+) T cells, and CD2 down-modulation

Anti-CD2 MoAbs have previously been shown to induce tolerance and to block B cell differentiation, T cell and monocyte activation. Since these immune functions are important in joint inflammation, we asked whether administration of the anti-CD2 MoAb OX34 has a beneficial effect on established rat ad...

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Autori principali: HOFFMANN, J C, HERKLOTZ, C, ZEIDLER, H, BAYER, B, WESTERMANN, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904785/
https://ncbi.nlm.nih.gov/pubmed/9353150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4881385.x
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