Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross-reactive autoantibodies to tyrosinase and tyrosinase-related protein-2 (TRP-2)

In the present study we describe the detection of TRP-2 antibodies in vitiligo patients using in vitro(35)S-labelled human TRP-2 in a radioimmunoassay. Of 53 vitiligo sera examined in the assay, three (5.9%) were found to be positive for TRP-2 antibodies. In contrast, 20 control sera, sera from 10 p...

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Hlavní autoři: KEMP, E H, GAWKRODGER, D J, WATSON, P F, WEETMAN, A P
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 1997
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904761/
https://ncbi.nlm.nih.gov/pubmed/9328128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4781381.x
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