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Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes.

Genetic and biochemical studies have provided convincing evidence that the 5' noncoding region (5' NCR) of hepatitis C virus (HCV) is highly conserved among viral isolates worldwide and that translation of HCV is directed by an internal ribosome entry site (IRES) located within the 5' NCR. We have i...

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Udgivet i:J Virol
Principais autores: Hanecak, R, Brown-Driver, V, Fox, M C, Azad, R F, Furusako, S, Nozaki, C, Ford, C, Sasmor, H, Anderson, K P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8764029/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.5203-5212.1996
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