Hyperexpression of transporter in antigen processing-1 (TAP-1) in thyroid glands affected by autoimmunity: a contributory factor to the breach of tolerance to thyroid antigens?

According to the ‘aberrant HLA expression’ hypothesis, endocrine autoimmunity is driven by presentation of self antigens by target cells over-expressing HLA molecules. In autoimmune thyroid diseases (AITD), thyroid follicular cells (thyrocytes) over-express HLA class I and HLA class II molecules. Si...

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Main Authors: SOSPEDRA, M, TOLOSA, E, ARMENGOL, P, ASHHAB, Y, URLINGER, S, LUCAS-MARTIN, A, FOZ-SALA, M, JARAQUEMADA, D, PUJOL-BORRELL, R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904729/
https://ncbi.nlm.nih.gov/pubmed/9218831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.3811277.x
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