Role of tumour necrosis factor-alpha (TNF-α) in the induction of HIV-1 gp120-mediated CD4(+) T cell anergy

The HIV-1 envelope glycoprotein (gp120) is known to induce antigen-specific and non-specific CD4(+) T cell anergy. We found that early T cell activation, as indicated by HLA-DP expression in the early G(1) (G(1A)) phase of the cell cycle, and the inhibition of mitogen-mediated IL-2 production induce...

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Detalhes bibliográficos
Main Authors: KANEKO, H, HISHIKAWA, T, SEKIGAWA, I, HASHIMOTO, H, OKUMURA, K, KANEKO, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904728/
https://ncbi.nlm.nih.gov/pubmed/9218822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4231325.x
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