Protective effect of granulocyte colony-stimulating factor (G-CSF) in a granulocytopenic mouse model of Pseudomonas aeruginosa lung infection through enhanced phagocytosis and killing by alveolar macrophages through priming tumour necrosis factor-alpha (TNF-α) production

We investigated the effects of G-CSF in a granulocytopenic mouse model of Pseudomonas aeruginosa lung infection. The model was prepared by intratracheal instillation of the bacteria, while granulocytopenia was induced by intraperitoneal injection of 4.0 mg of cyclophosphamide (CPA). There was no dif...

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Bibliographische Detailangaben
Hauptverfasser: SHIRAI, R, KADOTA, J, TOMONO, K, OGAWA, K, IIDA, K, KAWAKAMI, K, KOHNO, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1997
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904725/
https://ncbi.nlm.nih.gov/pubmed/9218827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4211317.x
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