Specificity and immunochemical properties of antibodies to bacterial DNA in sera of normal human subjects and patients with systemic lupus erythematosus (SLE)

To elucidate the mechanisms of anti-DNA production, we assessed the binding of sera of normal human subjects (NHS) and patients with SLE to a panel of bacterial and mammalian DNA. Using single-stranded DNA as antigens in an ELISA, NHS showed significant binding to some but not all bacterial DNA, whi...

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Detalhes bibliográficos
Main Authors: WU, Z-Q, DRAYTON, D, PISETSKY, D S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Editorial Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904712/
https://ncbi.nlm.nih.gov/pubmed/9218820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4301328.x
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