Evidence for genetic heterogeneity in inflammatory bowel disease (IBD); HLA genes in the predisposition to suffer from ulcerative colitis (UC) and Crohn's disease (CD)

Family and epidemiological studies support a genetic susceptibility to UC and CD. Conflicting reports regarding associations between UC and HLA-DR2 and between CD and various HLA alleles have been published. The aim of this study was to determine whether molecularly defined HLA-DR genes are associat...

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Detalhes bibliográficos
Main Authors: BOUMA, G, OUDKERK POOL, M, CRUSIUS, J B A, SCHREUDER, G M TH, HELLEMANS, H P R, MEIJER, B U G A, KOSTENSE, P J, GIPHART, M J, MEUWISSEN, S G M, PEÑA, A S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904705/
https://ncbi.nlm.nih.gov/pubmed/9218841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4121510.x
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