The systemic lupus erythematosus (SLE) disease autoantigen—calreticulin can inhibit C1q association with immune complexes

Following its release from cells during infection and inflammation, calreticulin (CRT) can act as an autoantigen in diseases such as SLE. Why CRT is a target of protective immunity and whether it may interfere with innate immunity once released from cells during inflammation is unclear. In the prese...

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Autors principals: KISHORE, U, SONTHEIMER, R D, SASTRY, K N, ZAPPI, E G, HUGHES, G R V, KHAMASHTA, M A, REID, K B M, EGGLETON, P
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1997
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904655/
https://ncbi.nlm.nih.gov/pubmed/9158084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.3761273.x
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