IL-12 inhibits in vitro immunoglobulin production by human lupus peripheral blood mononuclear cells (PBMC)

Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease characterized by polyclonal B cell activation and by the production of anti-double-stranded (ds) DNA antibodies. Given the inhibitory effects of IL-12 on humoral immune responses, we investigated whether IL-12 displayed such an...

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Main Authors: HOUSSIAU, F A, MASCART-LEMONE, F, STEVENS, M, LIBIN, M, DEVOGELAER, J-P, GOLDMAN, M, RENAULD, J-C
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1997
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904652/
https://ncbi.nlm.nih.gov/pubmed/9158113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.d01-1009.x
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