HIV infection of CD45RA(+) and CD45RO(+) CD4(+) T cells

HIV preferentially infects the RO(+) memory subset of CD4(+) lymphocytes, and these cells are lost earlier in HIV infection than their RA(+) counterparts. Although both populations express similar amounts of CD4 and bind the HIV envelope glycoprotein (gp120) equally well, calcium signals and CD4 dow...

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Detalhes bibliográficos
Main Authors: HELBERT, M R, WALTER, J, L'AGE, J, BEVERLEY, P C L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904594/
https://ncbi.nlm.nih.gov/pubmed/9030867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.1997.280-ce1170.x
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