Tumour cell killing using chemically engineered antibody constructs specific for tumour cells and the complement inhibitor CD59

Immunotherapy using MoAbs is inefficient due to limited activation of human effectors by mouse antibodies and multiple protective mechanisms available to host cells against autologous complement. We have used chemically engineered antibody constructs and human complement in vitro to specifically tar...

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Bibliografiska uppgifter
Huvudupphovsmän: HARRIS, C L, KAN, K S, STEVENSON, G T, MORGAN, B P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 1997
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904584/
https://ncbi.nlm.nih.gov/pubmed/9030877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.1997.265-ce1156.x
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