The effects of vitamin A derivatives on in vitro antibody production by peripheral blood mononuclear cells (PBMC) from normal blood donors and patients with common variable immunodeficiency (CVID)

The underlying nature of the defect of CVID is not understood, and the treatment at present is life-long infusion of replacement immunoglobulin. Attempts have been made to use other therapeutic agents, such as IL-2 and retinoic acid (RA), with mixed results. RA is a morphogenetic signalling molecule...

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Autores principales: ZHANG, J-G, MORGAN, L, SPICKETT, G P
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1997
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904540/
https://ncbi.nlm.nih.gov/pubmed/9010257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.d01-893.x
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