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Class II MHC antigen presentation defect in neonatal monocytes is not correlated with decreased MHC-II expression

Neonates are at increased risk of infections compared to adults. To dissect the mechanisms that contribute to neonatal immune deficiency, we compared MHC-II antigen processing and presentation by monocytes from umbilical cord blood and unrelated adult controls. Antigen-specific, costimulation-indepe...

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Bibliografische gegevens
Hoofdauteurs: Canaday, David H., Chakravarti, Soma, Srivastava, Tarun, Tisch, Daniel J., Cheruvu, Vinay K., Harding, Clifford V., Ramachandra, Lakshmi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904503/
https://ncbi.nlm.nih.gov/pubmed/17324388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2007.01.003
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