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Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

Despite the formidable mutational capacity and sequence diversity of HIV-1, evidence suggests that viral evolution in response to specific selective pressures follows generally predictable mutational pathways. Population-based analyses of clinically derived HIV sequences may be used to identify immu...

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Detalhes bibliográficos
Main Authors: Brumme, Zabrina L, Brumme, Chanson J, Heckerman, David, Korber, Bette T, Daniels, Marcus, Carlson, Jonathan, Kadie, Carl, Bhattacharya, Tanmoy, Chui, Celia, Szinger, James, Mo, Theresa, Hogg, Robert S, Montaner, Julio S. G, Frahm, Nicole, Brander, Christian, Walker, Bruce D, Harrigan, P. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904471/
https://ncbi.nlm.nih.gov/pubmed/17616974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030094
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