Inhibition of Smooth Muscle Proliferation by Urea-Based Alkanoic Acids via Peroxisome Proliferator-Activated Receptor α–Dependent Repression of Cyclin D1

OBJECTIVE: Proliferation of smooth muscle cells is implicated in cardiovascular complications. Previously, a urea-based soluble epoxide hydrolase inhibitor was shown to attenuate smooth muscle cell proliferation. We examined the possibility that urea-based alkanoic acids activate the nuclear recepto...

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Detaylı Bibliyografya
Asıl Yazarlar: Ng, Valerie Y., Morisseau, Christophe, Falck, John R., Hammock, Bruce D., Kroetz, Deanna L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904341/
https://ncbi.nlm.nih.gov/pubmed/16917105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.ATV.0000242013.29441.81
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