Replacement of the essential Dictyostelium Arp2 gene by its Entamoeba homologue using parasexual genetics

BACKGROUND: Cell motility is an essential feature of the pathogenesis and morbidity of amoebiasis caused by Entamoeba histolytica. As motility depends on cytoskeletal organisation and regulation, a study of the molecular components involved is key to a better understanding of amoebic pathogenesis. H...

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Main Authors: Zaki, Mehreen, King, Jason, Fütterer, Klaus, Insall, Robert H
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904233/
https://ncbi.nlm.nih.gov/pubmed/17553170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-28
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