Loading...

Coupling of hydrogenic tunneling to active-site motion in the hydrogen radical transfer catalyzed by a coenzyme B(12)-dependent mutase

Hydrogen transfer reactions catalyzed by coenzyme B(12)-dependent methylmalonyl-CoA mutase have very large kinetic isotope effects, indicating that they proceed by a highly quantal tunneling mechanism. We explain the kinetic isotope effect by using a combined quantum mechanical/molecular mechanical...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Dybala-Defratyka, Agnieszka, Paneth, Piotr, Banerjee, Ruma, Truhlar, Donald G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904141/
https://ncbi.nlm.nih.gov/pubmed/17581872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702188104
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!