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An empirical test of the concomitantly variable codon hypothesis

A central assumption of models of molecular evolution, that each site in a sequence evolves independently of all other sites, lacks empirical support. We investigated the extent to which sites evolve codependently in triosephosphate isomerase (TIM), a ubiquitous glycolytic enzyme conserved in both s...

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Detalhes bibliográficos
Main Authors: Merlo, Lauren M. F., Lunzer, Mark, Dean, Antony M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904112/
https://ncbi.nlm.nih.gov/pubmed/17578921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701900104
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