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An empirical test of the concomitantly variable codon hypothesis
A central assumption of models of molecular evolution, that each site in a sequence evolves independently of all other sites, lacks empirical support. We investigated the extent to which sites evolve codependently in triosephosphate isomerase (TIM), a ubiquitous glycolytic enzyme conserved in both s...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904112/ https://ncbi.nlm.nih.gov/pubmed/17578921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701900104 |
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