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The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function.

Human immunodeficiency virus types 1 and 2 encode closely related proteins, Tat-1 and Tat-2, that stimulate viral transcription. Previously, we showed that the activation domains of these proteins specifically interact in vitro with a cellular protein kinase named TAK. In vitro, TAK phosphorylates t...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Yang, X, Herrmann, C H, Rice, A P
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4576-4584.1996
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