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Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells.

A major impediment to the effective use of adenovirus vectors for gene therapy is a lack of knowledge of how these vectors interact with diverse cell types in vivo. Adenovirus attachment to most human cell types is mediated by the fiber protein, which binds to an as yet unidentified cell receptor. I...

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Bibliografiske detaljer
Main Authors: Huang, S, Kamata, T, Takada, Y, Ruggeri, Z M, Nemerow, G R
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC190385/
https://ncbi.nlm.nih.gov/pubmed/8676475
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