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An in vitro model of pancreas carcinogenesis: two-stage MNU--TPA effect.

Organ-cultured embryonic rat pancreata were exposed to either single or multiple doses of methylnitrosourea (MNU), a single dose of MNU followed by 12-O-tetradecanoyl-phorbol-13-acetate (TPA), or TPA alone and cultured for up to 6 weeks. Both single and multiple doses of MNU caused similar alteratio...

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Main Authors: Parsa, I., Marsh, W. H., Sutton, A. L.
Format: Artigo
Jezik:Inglês
Izdano: 1980
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1903507/
https://ncbi.nlm.nih.gov/pubmed/7361849
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