Defective alpha-granule production in megakaryocytes from gray platelet syndrome: ultrastructural studies of bone marrow cells and megakaryocytes growing in culture from blood precursors.

The ultrastructure and cytochemistry of megakaryocytes from two patients with a familial gray platelet syndrome are described. Although the Golgi zones appeared normally developed, the megakaryocytes lacked alpha-granules. Catalase-containing particles were normal in number. In immature megakaryocyt...

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Hauptverfasser: Breton-Gorius, J., Vainchenker, W., Nurden, A., Levy-Toledano, S., Caen, J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1903440/
https://ncbi.nlm.nih.gov/pubmed/7468753
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