Clindamycin, erythromycin, and roxithromycin inhibit the proinflammatory interactions of Pseudomonas aeruginosa pigments with human neutrophils in vitro.

The Pseudomonas aeruginosa-derived phenazine pigments pyocyanin and 1-hydroxyphenazine (1-hp) prime human neutrophils for enhanced, stimulus-activated release of superoxide and myeloperoxidase (MPO), respectively. In the present study, the modulatory potentials of the antimicrobial agents clindamyci...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Ras, G J, Anderson, R, Taylor, G W, Savage, J E, van Niekerk, E, Joone, G, Koornhof, H J, Saunders, J, Wilson, R, Cole, P J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.6.1236
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