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Evidence that replication of human neurotropic JC virus DNA in glial cells is regulated by the sequence-specific single-stranded DNA-binding protein Pur alpha.

Initiation of polyomavirus DNA replication in eukaryotic cells requires the participation of the viral early protein T antigen, cellular replication factors, and DNA polymerases. The human polyomavirus JC virus (JCV) is the etiologic agent of the fatal demyelinating disease progressive multifocal le...

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Bibliografische gegevens
Hoofdauteurs: Chang, C F, Gallia, G L, Muralidharan, V, Chen, N N, Zoltick, P, Johnson, E, Khalili, K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC190307/
https://ncbi.nlm.nih.gov/pubmed/8648759
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