Evidence that replication of human neurotropic JC virus DNA in glial cells is regulated by the sequence-specific single-stranded DNA-binding protein Pur alpha.

Initiation of polyomavirus DNA replication in eukaryotic cells requires the participation of the viral early protein T antigen, cellular replication factors, and DNA polymerases. The human polyomavirus JC virus (JCV) is the etiologic agent of the fatal demyelinating disease progressive multifocal le...

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Pubblicato in:	J Virol
Autori principali:	Chang, C F, Gallia, G L, Muralidharan, V, Chen, N N, Zoltick, P, Johnson, E, Khalili, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190307/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.4150-4156.1996
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