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Induction of interleukin-12 (IL-12) by recombinant glycoprotein gp120 of human immunodeficiency virus type 1 in human monocytes/macrophages: requirement of gamma interferon for IL-12 secretion.

We studied the effects of the gp120 glycoprotein of human immunodeficiency virus type 1 on the expression of interleukin-12 (IL-12) in human monocytes and in monocyte-derived macrophages. Induction of the mRNA for both the p35 and p40 subunits of IL-12 was observed in both cell types after gp120 tre...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Fantuzzi, L, Gessani, S, Borghi, P, Varano, B, Conti, L, Puddu, P, Belardelli, F
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1996
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190299/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.4121-4124.1996
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