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Targeting human immunodeficiency virus type 1 reverse transcriptase by intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle.

Novel molecular approaches to inhibit human immunodeficiency virus type 1 (HIV-1) infection have received increasing attention because of the lack of effective antiviral drug therapies in vivo. We now demonstrate that cells can be intracellularly immunized by cytoplasmic expression of single-chain v...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Virol
Principais autores: Shaheen, F, Duan, L, Zhu, M, Bagasra, O, Pomerantz, R J
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 1996
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648670/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3392-3400.1996
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