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Inhibition of human and simian immunodeficiency virus protease function by targeting Vpx-protease-mutant fusion protein into viral particles.

The human immunodeficiency virus type I (HIV-1) Vpr and HIV-2 Vpx proteins package into virions through interactions with their cognate Gag polyprotein precursor. The targeting properties of Vpr and Vpx have been exploited to incorporate foreign proteins into virions by expression as heterologous fu...

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Udgivet i:J Virol
Principais autores: Wu, X, Liu, H, Xiao, H, Conway, J A, Kappes, J C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3378-3384.1996
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