Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques.

By animal-to-animal passage of simian/human immunodeficiency virus (SHIV) in pig-tailed macaques, we have developed a macaque model of human immunodeficiency virus type 1 (HIV-1) disease in humans. Passaging was begun with a chimeric virus containing the env gene of HIV-1 HXBc2 and the gag and pol g...

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Detalhes bibliográficos
Main Authors: Joag, S V, Li, Z, Foresman, L, Stephens, E B, Zhao, L J, Adany, I, Pinson, D M, McClure, H M, Narayan, O
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190182/
https://ncbi.nlm.nih.gov/pubmed/8627799
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