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Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
Peptide nucleic acids (PNAs) can bind to single-stranded DNA by Watson–Crick base pairing and can form triple helices via Hoogsteen bonding to DNA/PNA duplexes. A single dimeric PNA molecule can form a clamp via both double- and triple-helix formation. We designed PNAs to bind as clamps to a site in...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The National Academy of Sciences
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC19018/ https://ncbi.nlm.nih.gov/pubmed/9465026 |
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