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Sindbis virus RNA-negative mutants that fail to convert from minus-strand to plus-strand synthesis: role of the nsP2 protein.

We identified mutations in the gene for nsP2, a nonstructural protein of the alphavirus Sindbis virus, that appear to block the conversion of the initial, short-lived minus-strand replicase complex (RCinitial) into mature, stable forms that are replicase and transcriptase complexes (RCstable), produ...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Dé, I, Sawicki, S G, Sawicki, D L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190127/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627744/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.5.2706-2719.1996
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