Genetic analysis of the zinc finger in the Moloney murine leukemia virus nucleocapsid domain: replacement of zinc-coordinating residues with other zinc-coordinating residues yields noninfectious particles containing genomic RNA.

The effect of changing zinc (Zn2+)-coordinating residues in the nucleocapsid protein of Moloney murine leukemia virus was investigated by introducing a His-34-to-Cys or Cys-39-to-His mutation into the putative Zn2+ finger. Mutant virions contained normal levels of properly processed Gag and Env prot...

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Publié dans:	J Virol
Auteurs principaux:	Gorelick, R J, Chabot, D J, Ott, D E, Gagliardi, T D, Rein, A, Henderson, L E, Arthur, L O
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2593-2597.1996
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