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The noncoding and surface envelope coding sequences of myeloblastosis-associated virus are respectively responsible for nephroblastoma development and renal hyperplasia.

The use of chimeric viruses allowed us to establish that myeloblastosis-associated virus long terminal repeat sequences are necessary and sufficient for induction of nephroblastoma in chickens and that the blastemal hyperplasia induced by env SU is not a prerequisite for tumor development but rather...

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Bibliographic Details
Published in:J Virol
Main Authors: Joliot, V, Khelifi, C, Wyers, M, Dambrine, G, Lasserre, F, Lemercier, P, Perbal, B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190104/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2576-2580.1996
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