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A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation.

Latency-associated transcript (LAT) promoter deletion mutants of herpes simplex virus type 1 have a reduced capacity to reactivate following adrenergic induction in the rabbit eye model. We have mapped a reactivation phenotype within LAT and describe the construction of recombinants in which poly(A)...

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Udgivet i:J Virol
Principais autores: Bloom, D C, Hill, J M, Devi-Rao, G, Wagner, E K, Feldman, L T, Stevens, J G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2449-2459.1996
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